close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB14013.1Succinate-semialdehyde dehydrogenase [NADP+]. (411 aa)    
Predicted Functional Partners:
AKB12140.1
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.948
AKB12620.1
Succinate dehydrogenase flavoprotein subunit.
  
 0.938
AKB12621.1
Succinate dehydrogenase iron-sulfur protein.
  
 
 0.927
AKB14275.1
Succinate-semialdehyde dehydrogenase [NADP+].
  
  
 
0.901
AKB12618.1
Succinate-semialdehyde dehydrogenase [NADP+].
  
  
 
0.900
AKB13796.1
Citrate synthase (si).
  
 0.898
AKB13041.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.845
AKB13346.1
3-isopropylmalate dehydrogenase.
   
 0.837
AKB14284.1
2-oxoglutarate oxidoreductase, alpha subunit.
   
 0.836
AKB13992.1
Pyruvate carboxyl transferase subunit A.
   
 0.834
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
Server load: low (32%) [HD]