Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB14026.1Geranylfarnesyl diphosphate synthetase; Belongs to the FPP/GGPP synthase family. (285 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
 
 0.979
AKB13879.1
Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
0.918
AKB14027.1
Metallo cofactor biosynthesis protein.
       0.863
AKB13499.1
Undecaprenyl diphosphate synthase.
 
  
 0.754
AKB12496.1
Hypothetical protein.
 
  
 0.697
rnj
Putative Zn-dependent hydrolase in polyisoprenoid biosynthetic cluster; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
  
    0.678
AKB11965.1
NADH-quinone oxidoreductase subunit C/D.
 
  
 0.644
AKB14285.1
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
  
 
 0.641
AKB11964.1
NADH-quinone oxidoreductase subunit C/D.
  
  
 0.595
tatC-2
Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
  
 0.589
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.