Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB14272.1FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. (168 aa)    
Predicted Functional Partners:
AKB14270.1
OB-fold nucleic acid binding domain protein.
       0.641
AKB12560.1
Ni2+-binding GTPase involved in regulation of expression and maturation of hydrogenase.
    
 
 0.552
AKB12881.1
[NiFe] hydrogenase nickel incorporation-associated protein HypB.
    
 
 0.552
AKB14273.1
Membrane protein, putative.
       0.550
AKB14271.1
Peptidyl-prolyl cis-trans isomerase.
 
    
0.527
AKB14060.1
Energy-conserving hydrogenase (ferredoxin), subunit E.
    
 
 0.500
rps10
SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
  
 0.463
tuf
Translation elongation factor 1 alpha subunit; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
   
  
 0.451
rps3ae
SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
   
    0.441
fusA
Translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
  
  
 0.434
Your Current Organism:
Methanosarcina thermophila
NCBI taxonomy Id: 523844
Other names: M. thermophila TM-1, Methanosarcina thermophila OCM 12, Methanosarcina thermophila TM-1, Methanosarcina thermophila str. TM-1, Methanosarcina thermophila strain TM-1
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