STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0014Protein of unknown function DUF116; COGs: COG1852 conserved hypothetical protein; InterPro IPR002829; KEGG: mth:MTH559 hypothetical protein; PFAM: protein of unknown function DUF116; SPTR: O26659 Conserved protein; PFAM: Protein of unknown function DUF116. (212 aa)    
Predicted Functional Partners:
Mfer_0015
KEGG: mtp:Mthe_1014 hypothetical protein; SPTR: B9ACT4 Putative uncharacterized protein.
       0.803
Mfer_0016
KEGG: msi:Msm_0223 hypothetical protein; SPTR: A5UJQ0 Putative uncharacterized protein.
       0.801
Mfer_0560
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
     0.511
Mfer_0006
Protein of unknown function UPF0179; COGs: COG1860 conserved hypothetical protein; InterPro IPR005369; KEGG: mth:MTH609 hypothetical protein; PFAM: Protein of unknown function UPF0179; SPTR: P72011 UPF0179 protein MTH_609; PFAM: Uncharacterised protein family (UPF0179); Belongs to the UPF0179 family.
  
   
 0.471
Mfer_0561
InterPro IPR006058; KEGG: tte:TTE1329 hypothetical protein; SPTR: C6P811 Putative uncharacterized protein.
  
     0.451
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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