STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0059ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: mth:MTH606 manganese transport system membrane protein; PFAM: ABC-3 protein; SPTR: O26706 Manganese transport system membrane protein; PFAM: ABC 3 transport family. (265 aa)    
Predicted Functional Partners:
Mfer_0060
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: mth:MTH605 ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: O26705 ABC transporter; PFAM: ABC transporter.
 0.999
Mfer_0061
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127: IPR006128: IPR006129; KEGG: mth:MTH604 adhesion protein; PFAM: periplasmic solute binding protein; SPTR: O26704 Adhesion protein; PFAM: Periplasmic solute binding protein family.
 
 0.996
Mfer_0555
ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439: IPR003593: IPR017871; KEGG: dau:Daud_1150 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B1I446 ABC transporter related; PFAM: ABC transporter.
 
 0.956
Mfer_0057
InterPro IPR004298; KEGG: mth:MTH675 hypothetical protein; SPTR: B9ADE3 Putative uncharacterized protein; PFAM: Nicotianamine synthase protein.
       0.768
Mfer_0058
KEGG: mth:MTH677 hypothetical protein; SPTR: O26773 Uncharacterized protein MTH_677; PFAM: Protein of unknown function (DUF3194).
       0.768
Mfer_0556
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006129: IPR006127; KEGG: dau:Daud_1151 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: B1I429 Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family.
 
  
 0.762
Mfer_0056
Like-Sm ribonucleoprotein core; InterPro IPR010920: IPR001163: IPR006649; KEGG: mth:MTH1440 hypothetical protein; PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein; SPTR: O27489 Putative uncharacterized protein; PFAM: LSM domain.
       0.704
Mfer_0062
COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR010985: IPR002145: IPR014864: IPR013321; KEGG: mth:MTH603 hypothetical protein; PFAM: NikR nickel binding; CopG domain protein DNA-binding domain protein; SPTR: O26703 Putative nickel-responsive regulator 1; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain.
     
 0.615
Mfer_0191
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367: IPR008988: IPR007167; KEGG: mth:MTH214 iron repressor; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: O26316 Iron repressor; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
  
 0.487
Mfer_0553
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR006162: IPR001626; KEGG: dau:Daud_1149 ABC-3 protein; PFAM: ABC-3 protein; SPTR: B1I445 ABC-3 protein; PFAM: ABC 3 transport family.
  
  
 
0.480
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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