STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0140Hypothetical protein; KEGG: cbb:CLD_2405 CRISPR-associated RAMP protein; SPTR: C7GHY9 Alfa-L-rhamnosidase. (81 aa)    
Predicted Functional Partners:
Mfer_0138
COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: mth:MTH1854 hypothetical protein; PFAM: amino acid-binding ACT domain protein; SPTR: O27882 Putative uncharacterized protein; PFAM: ACT domain.
       0.547
Mfer_0139
KEGG: mka:MK0367 hypothetical protein; SPTR: Q8TYD3 Uncharacterized protein conserved in archaea.
       0.547
secE
Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
       0.539
spt5
LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
       0.488
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
       0.488
rpl1
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
       0.451
rpl10
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
       0.451
rpl12
LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
       0.417
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.417
Mfer_0148
Methanogenesis marker 16 metalloprotein; COGs: COG1900 conserved hypothetical protein; InterPro IPR017896: IPR002708: IPR017677; KEGG: msi:Msm_0085 putative ferredoxin; PFAM: protein of unknown function DUF39; SPTR: B9AD65 Putative uncharacterized protein; TIGRFAM: methanogenesis marker 16 metalloprotein; PFAM: Domain of unknown function DUF39; TIGRFAM: putative methanogenesis marker 16 metalloprotein.
       0.417
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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