STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0170DNA-binding TFAR19-related protein; InterPro IPR002836; KEGG: mth:MTH1615 hypothetical protein; PFAM: DNA-binding TFAR19-related protein; SPTR: O27652 DNA-binding protein MTH_1615; PFAM: Double-stranded DNA-binding domain; Belongs to the PDCD5 family. (114 aa)    
Predicted Functional Partners:
Mfer_0169
Queuosine synthesis; COGs: COG2117 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR018317: IPR014729; KEGG: mth:MTH1614 hypothetical protein; PFAM: Queuosine synthesis-like; SPTR: O27651 Conserved protein; PFAM: ExsB.
  
    0.974
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
    0.969
pfdA
Prefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
   0.950
rpl39e
LSU ribosomal protein L39E; InterPro IPR000077; KEGG: pab:PAB3384 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; SPTR: Q9UYI8 50S ribosomal protein L39e; PFAM: Ribosomal L39 protein; Belongs to the eukaryotic ribosomal protein eL39 family.
 
    0.945
rpl31e
COGs: COG2097 Ribosomal protein L31E; InterPro IPR000054: IPR020052; KEGG: mth:MTH1612 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: O27649 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
    0.941
eif6
Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
    0.901
rpl1
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
  
 0.887
rps24e
COGs: COG2004 Ribosomal protein S24E; InterPro IPR001976: IPR012677; KEGG: mth:MTH267 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; SPTR: O26367 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.886
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
    0.874
rpl30e
COGs: COG1911 Ribosomal protein L30E; InterPro IPR000231: IPR004038; KEGG: mth:MTH1053 50S ribosomal protein L30e; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: O27127 50S ribosomal protein L30e; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Belongs to the eukaryotic ribosomal protein eL30 family.
  
    0.857
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.