STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnp4Ribonuclease P protein subunit Rpp21; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (120 aa)    
Predicted Functional Partners:
rnp3
Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
 0.999
rnp2
Ribonuclease P-related protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
   
 0.989
rnp1
Ribonuclease P protein subunit Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
  
 
 0.985
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.983
rps4
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.980
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
   
 
 0.979
rps11
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 
 0.976
Mfer_0294
RIO-like kinase; COGs: COG1718 Serine/threonine protein kinase involved in cell cycle control; InterPro IPR011009: IPR000719: IPR018934: IPR000687; KEGG: mth:MTH1005 hypothetical protein; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1; SPTR: O27086 Conserved protein; PFAM: RIO1 family.
   
 
  0.915
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
  
  0.873
Mfer_0172
Protein of unknown function UPF0044; InterPro IPR001890; KEGG: mst:Msp_0593 hypothetical protein; PFAM: protein of unknown function UPF0044; SPTR: Q2NGR2 Putative uncharacterized protein; PFAM: CRS1 / YhbY (CRM) domain.
       0.870
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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