STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0196COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: mth:MTH138 GlcNAc-phosphatidylinositol related biosynthetic protein; PFAM: glycosyl transferase group 1; SPTR: O26241 GlcNAc-phosphatidylinositol related biosynthetic protein; PFAM: Glycosyl transferases group 1. (378 aa)    
Predicted Functional Partners:
Mfer_0198
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: mst:Msp_0541 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: Q2NGW3 Predicted glycosyltransferase; PFAM: Glycosyl transferase family 2.
 
 
 0.857
Mfer_0199
NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005829: IPR005025; KEGG: mth:MTH135 hypothetical protein; PFAM: NADPH-dependent FMN reductase; SPTR: O26238 Conserved protein; PFAM: NADPH-dependent FMN reductase.
 
  
 0.812
Mfer_0197
Protein of unknown function DUF2304; COGs: COG2456 conserved hypothetical protein; InterPro IPR019277; KEGG: mth:MTH137 hypothetical protein; PFAM: Protein of unknown function DUF2304; SPTR: O26240 Uncharacterized protein MTH_137; PFAM: Uncharacterized conserved protein (DUF2304).
     
 0.794
Mfer_0200
COGs: COG1731 riboflavin synthase; InterPro IPR002180: IPR006399; KEGG: mth:MTH134 riboflavin synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; PRIAM: Riboflavin synthase; SPTR: Q59587 Riboflavin synthase; TIGRFAM: riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: riboflavin synthase.
       0.740
ecfA
Cobalt ABC transporter, ATPase subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
     
 0.729
Mfer_0361
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011051: IPR005835: IPR013096; KEGG: mth:MTH1523 glucose-1-phosphate adenylyltransferase related protein; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; SPTR: O27567 Glucose-1-phosphate adenylyltransferase related protein; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase.
  
 
 0.716
Mfer_1077
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: mth:MTH370 LPS biosynthesis RfbU related protein; PFAM: glycosyl transferase group 1; SPTR: O26470 LPS biosynthesis RfbU related protein; PFAM: Glycosyl transferases group 1.
  
     0.672
Mfer_0280
NAD-dependent epimerase/dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR016040: IPR006141: IPR004042: IPR001509: IPR 003586: IPR006142; KEGG: mth:MTH1789 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SMART: Hedgehog/intein hint domain protein; SPTR: B5IVN1 dTDP-glucose 4,6-dehydratase, putative; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region; dTDP-glucose 4,6-dehydratase.
 
  
 0.659
Mfer_0468
COGs: COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase; InterPro IPR005262: IPR001173: IPR007235; KEGG: mth:MTH884 teichoic acid biosynthesis related protein; PFAM: glycosyl transferase family 2; Glycosyltransferase 28 domain; SPTR: O26970 Teichoic acid biosynthesis related protein; PFAM: Glycosyltransferase family 28 C-terminal domain; Glycosyl transferase family 2; TIGRFAM: conserved hypothetical protein.
 
 0.648
Mfer_0281
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.646
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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