STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0285COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR016040: IPR005913; KEGG: mth:MTH1792 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; SPTR: O27820 DTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase. (280 aa)    
Predicted Functional Partners:
Mfer_0281
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
Mfer_0280
NAD-dependent epimerase/dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR016040: IPR006141: IPR004042: IPR001509: IPR 003586: IPR006142; KEGG: mth:MTH1789 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SMART: Hedgehog/intein hint domain protein; SPTR: B5IVN1 dTDP-glucose 4,6-dehydratase, putative; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region; dTDP-glucose 4,6-dehydratase.
 
 0.997
Mfer_0286
Glucose-1-phosphate thymidylyltransferase; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835: IPR005907; KEGG: mth:MTH1791 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; SPTR: O27819 Glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form; glucose-1-phosphate thymidylyltransferase, short form.
 
  
 0.988
Mfer_0361
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011051: IPR005835: IPR013096; KEGG: mth:MTH1523 glucose-1-phosphate adenylyltransferase related protein; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; SPTR: O27567 Glucose-1-phosphate adenylyltransferase related protein; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase.
  
  
 0.938
Mfer_0808
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR016040: IPR008089: IPR001509; KEGG: pmx:PERMA_1747 UDP-glucuronic acid decarboxylase 1 (UDP-glucuronatedecarboxylase 1) (UXS-1); PFAM: NAD-dependent epimerase/dehydratase; SPTR: A8URU5 UDP-glucuronate decarboxylase; PFAM: NAD dependent epimerase/dehydratase family.
  
 
 0.866
Mfer_0810
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR016040: IPR001509; KEGG: msi:Msm_0327 UDP-glucose 4-epimerase (NAD dependent); PFAM: NAD-dependent epimerase/dehydratase; SPTR: A5UK04 UDP-glucose 4-epimerase (NAD dependent); PFAM: NAD dependent epimerase/dehydratase family.
  
 
0.866
Mfer_1081
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR016040: IPR001509; KEGG: mth:MTH373 dTDP-glucose 4,6-dehydratase related protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: O26473 DTDP-glucose 4,6-dehydratase related protein; PFAM: NAD dependent epimerase/dehydratase family.
    
  0.807
Mfer_1072
COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: pab:PAB0795 rhamnosyl transferase related protein; PFAM: glycosyl transferase family 2; SPTR: Q9UZG0 Putative uncharacterized protein; PFAM: Glycosyl transferase family 2.
 
  
 0.780
Mfer_1275
COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005771: IPR005835; KEGG: mth:MTH634 UTP--glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; SPTR: O26731 UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
    
 0.770
Mfer_0468
COGs: COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase; InterPro IPR005262: IPR001173: IPR007235; KEGG: mth:MTH884 teichoic acid biosynthesis related protein; PFAM: glycosyl transferase family 2; Glycosyltransferase 28 domain; SPTR: O26970 Teichoic acid biosynthesis related protein; PFAM: Glycosyltransferase family 28 C-terminal domain; Glycosyl transferase family 2; TIGRFAM: conserved hypothetical protein.
  
  
 0.670
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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