STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0300(SSU ribosomal protein S18P)-alanine acetyltransferase; COGs: COG0456 Acetyltransferase; InterPro IPR016181: IPR000182: IPR006464; KEGG: mth:MTH999 N-terminal acetyltransferase complex, subunit ARD1; PFAM: GCN5-related N-acetyltransferase; SPTR: O27080 N-terminal acetyltransferase complex, subunit ARD1; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase. (143 aa)    
Predicted Functional Partners:
rpl23
LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
   0.831
rpl29
LSU ribosomal protein L29P; InterPro IPR018254: IPR001854; KEGG: mfe:Mefer_0690 ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: C7P7H7 Ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
    
 
 0.817
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR016185: IPR005480: IPR011761: IPR005479: IPR 005481: IPR011607: IPR013817: IPR013816: IPR005483: IPR006275; KEGG: msi:Msm_0488 carbamoylphosphate synthase, large subunit, CarB; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: O27077 Carbamoyl-phosphate synthase large chain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phospha [...]
  
 
 0.814
rpl3
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.814
rpl18
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
   0.814
rpl31e
COGs: COG2097 Ribosomal protein L31E; InterPro IPR000054: IPR020052; KEGG: mth:MTH1612 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: O27649 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
 
 0.810
rpl30e
COGs: COG1911 Ribosomal protein L30E; InterPro IPR000231: IPR004038; KEGG: mth:MTH1053 50S ribosomal protein L30e; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: O27127 50S ribosomal protein L30e; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Belongs to the eukaryotic ribosomal protein eL30 family.
   
 
 0.804
rpl24e
LSU ribosomal protein L24E; Binds to the 23S rRNA.
   
   0.802
Mfer_0870
COGs: COG1717 Ribosomal protein L32E; InterPro IPR018263: IPR001515; KEGG: mth:MTH20 50S ribosomal protein L32e; PFAM: Ribosomal protein L32e; SPTR: O26128 50S ribosomal protein L32e; PFAM: Ribosomal protein L32.
    
   0.800
rpl22
LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
   0.799
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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