STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0307Septum site-determining protein MinD; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR010224: IPR002586; KEGG: mth:MTH1840 cell division inhibitor; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: O27868 Cell division inhibitor; TIGRFAM: cell division ATPase MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: cell division ATPase MinD, archaeal. (258 aa)    
Predicted Functional Partners:
Mfer_0305
KEGG: mth:MTH1838 hypothetical protein; SPTR: O27866 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF552).
  
    0.805
Mfer_0308
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173: IPR002139: IPR011611; KEGG: mth:MTH1841 ribokinase; PFAM: PfkB domain protein; SPTR: O27869 Ribokinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family.
       0.783
Mfer_0306
Protein of unknown function DUF2226; InterPro IPR019249; KEGG: mth:MTH1839 hypothetical protein; PFAM: Protein of unknown function DUF2226; SPTR: O27867 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in archaea (DUF2226).
       0.782
Mfer_0304
Protein of unknown function DUF1611; COGs: COG3367 conserved hypothetical protein; InterPro IPR011669: IPR016040; KEGG: mth:MTH1837 hypothetical protein; PFAM: protein of unknown function DUF1611; SPTR: O27865 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1611).
       0.781
Mfer_0303
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: mth:MTH1836 hypothetical protein; PFAM: Roadblock/LC7 family protein; SPTR: O27864 Conserved protein; PFAM: Roadblock/LC7 domain.
 
    0.736
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.630
Mfer_0479
Type II secretion system protein E; COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: mth:MTH1702 secretory protein kinase; PFAM: type II secretion system protein E; SPTR: O27737 Secretory protein kinase; PFAM: Type II/IV secretion system protein.
  
  
 0.585
Mfer_1100
COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: mst:Msp_1571 ATPase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q2NE15 Predicted ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
  
0.577
Mfer_0478
Type II secretion system F domain protein; COGs: COG2064 Flp pilus assembly protein TadC; InterPro IPR018076; KEGG: mth:MTH1703 hypothetical protein; PFAM: Type II secretion system F domain; SPTR: O27738 Putative uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain.
 
  
 0.493
Mfer_0424
Peptidase A24A domain protein; InterPro IPR000045: IPR009639; KEGG: mth:MTH421 hypothetical protein; PFAM: Peptidase A24A domain protein; peptidase A24A prepilin type IV; SPTR: O26521 Uncharacterized protein MTH_421; PFAM: Type IV leader peptidase family; Archaeal Peptidase A24 C-terminal Domain.
     
 0.474
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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