STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif2gTranslation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa)    
Predicted Functional Partners:
rps6e
COGs: COG2125 Ribosomal protein S6E (S10); InterPro IPR018282: IPR001377; KEGG: mth:MTH260 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; SPTR: O26360 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
 
 0.998
eif2b
Translation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
 0.995
eif2a
Translation initiation factor 2 subunit alpha (aeIF-2a); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
  
 0.994
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.993
rps24e
COGs: COG2004 Ribosomal protein S24E; InterPro IPR001976: IPR012677; KEGG: mth:MTH267 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; SPTR: O26367 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 0.991
rps28e
COGs: COG2053 Ribosomal protein S28E/S33; InterPro IPR016027: IPR000289: IPR012340; KEGG: msi:Msm_0205 30S ribosomal protein S28e; PFAM: Ribosomal protein S28e; SPTR: A5UJN2 Ribosomal protein S28e; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 0.991
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR018281: IPR001593; KEGG: mth:MTH1593 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: O27630 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 0.985
eif1a
Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 0.985
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 0.985
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 0.984
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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