STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0493COGs: COG4007 dehydrogenase related to H2-forming N5 N10-methylenetetrahydromethanopterin dehydrogenase; InterPro IPR010063: IPR016040: IPR004889; KEGG: mth:MTH1512 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein; PFAM: H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase; SPTR: O27556 H(2)-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase homolog (II); TIGRFAM: coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; H2-forming N5,N [...] (341 aa)    
Predicted Functional Partners:
Mfer_0303
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: mth:MTH1836 hypothetical protein; PFAM: Roadblock/LC7 family protein; SPTR: O27864 Conserved protein; PFAM: Roadblock/LC7 domain.
  
    0.644
Mfer_0948
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: mth:MTH1836 hypothetical protein; PFAM: Roadblock/LC7 family protein; SPTR: O27864 Conserved protein; PFAM: Roadblock/LC7 domain.
  
    0.644
Mfer_0494
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR011059: IPR006680; KEGG: mth:MTH1534 aryldialkylphosphatase related protein; PFAM: amidohydrolase; SPTR: O27577 Aryldialkylphosphatase related protein; PFAM: Amidohydrolase family.
       0.467
Mfer_0495
Predicted aconitase subunit 2; COGs: COG1786 conserved hypothetical protein; InterPro IPR012016: IPR002840; KEGG: mth:MTH1530 hypothetical protein; PFAM: protein of unknown function DUF126; SPTR: O27573 UPF0107 protein MTH_1530; PFAM: Protein of unknown function DUF126; Belongs to the UPF0107 family.
       0.438
truD
tRNA pseudouridine synthase D TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
       0.410
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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