STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0558ATPase; KEGG: cth:Cthe_0434 ATPase; SPTR: A3DCJ3 ATPase. (352 aa)    
Predicted Functional Partners:
Mfer_0560
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
     0.887
Mfer_0561
InterPro IPR006058; KEGG: tte:TTE1329 hypothetical protein; SPTR: C6P811 Putative uncharacterized protein.
 
     0.886
Mfer_0557
COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mka:MK1323 beta-lactamase superfamily hydrolase; SPTR: Q8TVR5 Metal-dependent hydrolase of the beta-lactamase superfamily; PFAM: Metallo-beta-lactamase superfamily.
       0.773
Mfer_0559
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: mac:MA2155 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Q8TNX2 Putative uncharacterized protein; PFAM: Methyltransferase domain.
       0.773
Mfer_0562
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR001411: IPR016196: IPR011701; KEGG: mac:MA1657 efflux pump antibiotic resistance protein; PFAM: major facilitator superfamily MFS_1; SPTR: C8S7D4 Drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: Multidrug resistance protein.
       0.773
Mfer_0556
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006129: IPR006127; KEGG: dau:Daud_1151 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: B1I429 Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family.
 
     0.624
Mfer_0553
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR006162: IPR001626; KEGG: dau:Daud_1149 ABC-3 protein; PFAM: ABC-3 protein; SPTR: B1I445 ABC-3 protein; PFAM: ABC 3 transport family.
       0.476
Mfer_0554
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dau:Daud_1149 ABC-3 protein; PFAM: ABC-3 protein; SPTR: B1I445 ABC-3 protein; PFAM: ABC 3 transport family.
       0.476
Mfer_0555
ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439: IPR003593: IPR017871; KEGG: dau:Daud_1150 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B1I446 ABC transporter related; PFAM: ABC transporter.
       0.476
Mfer_0563
O-methyltransferase family 2; InterPro IPR001077; KEGG: dae:Dtox_0362 O-methyltransferase family 2; PFAM: O-methyltransferase family 2; SPTR: C8W4W2 O-methyltransferase family 2; PFAM: O-methyltransferase.
       0.461
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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