STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.998
asd
Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.995
Mfer_0421
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR019811: IPR016040: IPR005106: IPR001342; KEGG: msi:Msm_0154 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; SPTR: A5UJI1 Homoserine dehydrogenase, ThrA; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase.
  
 
 0.958
Mfer_0677
COGs: COG0527 Aspartokinase; InterPro IPR018042: IPR005260: IPR001341: IPR001048: IPR 002912; KEGG: mth:MTH802 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; PRIAM: Aspartate kinase; SPTR: O26893 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
 
  
 0.958
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.957
Mfer_0679
Chorismate mutase, type II; InterPro IPR020822: IPR002701; KEGG: mth:MTH804 chorismate mutase; PFAM: Chorismate mutase, type II; SPTR: O26895 Chorismate mutase, subunit A; PFAM: Chorismate mutase type II; TIGRFAM: chorismate mutase, archaeal type.
  
  
 0.942
rps17e
COGs: COG1383 Ribosomal protein S17E; InterPro IPR018273: IPR001210; KEGG: mth:MTH803 30S ribosomal protein S17e; PFAM: Ribosomal protein S17e; SPTR: O26894 30S ribosomal protein S17e; PFAM: Ribosomal S17; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.936
Mfer_0419
Asp/Glu amidotransferase, subunit C; InterPro IPR010120; KEGG: mth:MTH415 aspartyl/glutamyl-tRNA amidotransferase subunit C; SPTR: O26515 Conserved protein; TIGRFAM: Asp/Glu amidotransferase, subunit C; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase, subunit C, putative.
  
  
 0.859
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
 
  
 0.826
rps15
COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR000589: IPR009068: IPR012606; KEGG: mth:MTH1423 30S ribosomal protein S15P; PFAM: ribosomal protein S15; Ribosomal S13S15 domain protein; SPTR: O27474 30S ribosomal protein S15P/S13e; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15.
  
  
 0.776
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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