STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0718Haloacid dehalogenase domain protein hydrolase; COGs: COG4087 Soluble P-type ATPase; InterPro IPR001757: IPR005834; KEGG: mth:MTH1493 cation transporting P-type ATPase related protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: O27537 Cation transporting P-type ATPase related protein; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC. (265 aa)    
Predicted Functional Partners:
Mfer_0716
Translin; COGs: COG2178 RNA-binding protein of the translin family; InterPro IPR002848; KEGG: tsi:TSIB_0976 translin like protein; PFAM: Translin; SPTR: C6A339 Translin like protein; PFAM: Translin family.
       0.578
Mfer_0717
LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: ate:Athe_0312 LmbE family protein; PFAM: LmbE family protein; SPTR: B9MMZ6 LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase.
       0.578
Mfer_0719
Transcriptional regulator, XRE family; COGs: COG1813 transcription factor homolog of eukaryotic MBF1; InterPro IPR004451: IPR010982: IPR001387; KEGG: mth:MTH729 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: O26825 Conserved protein; PFAM: Helix-turn-helix; TIGRFAM: conserved hypothetical protein TIGR00270.
       0.543
Mfer_0721
Protein of unknown function DUF190; COGs: COG1993 conserved hypothetical protein; InterPro IPR015867: IPR011322: IPR003793; KEGG: ckr:CKR_0287 hypothetical protein; PFAM: protein of unknown function DUF190; SPTR: Q6E3B6 Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1993.
       0.541
crcB
Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.537
Mfer_0714
Conserved hypothetical protein; COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: mth:MTH1902 hypothetical protein; SPTR: O27924 UPF0173 metal-dependent hydrolase MTH_1902; PFAM: Metallo-beta-lactamase superfamily; Belongs to the UPF0173 family.
       0.473
Mfer_0715
KEGG: mth:MTH1901 hypothetical protein; SPTR: O27923 Putative uncharacterized protein.
       0.473
Mfer_0713
GTP-binding protein; COGs: COG0486 GTPase; InterPro IPR005225: IPR001806: IPR002917; KEGG: mth:MTH1903 hypothetical protein; PFAM: GTP-binding protein HSR1-related; SPTR: O27925 Putative uncharacterized protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
       0.433
Mfer_0712
COGs: COG3365 conserved hypothetical protein; InterPro IPR012017; KEGG: mth:MTH1904 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: O27926 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in archaea (DUF2073).
       0.411
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.