STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0735RNA-binding protein, predicted; InterPro IPR019300; KEGG: mth:MTH1128 hypothetical protein; PFAM: RNA-binding protein, predicted; SPTR: O27200 Uncharacterized protein MTH_1128; PFAM: Predicted RNA-binding protein. (59 aa)    
Predicted Functional Partners:
cdhD
acetyl-CoA decarbonylase/synthase delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
    0.716
Mfer_0524
Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR014433: IPR002586; KEGG: mth:MTH1711 nitrogenase reductase related protein; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: O27746 Nitrogenase reductase related protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
    0.609
Mfer_1042
Protein of unknown function DUF75; COGs: COG1938 protein of ATP-grasp superfamily; InterPro IPR002766: IPR004425; KEGG: mth:MTH1302 hypothetical protein; PFAM: protein of unknown function DUF75; SPTR: O27359 Conserved protein; PFAM: PAC2 family; TIGRFAM: conserved hypothetical protein TIGR00161.
      
 0.545
Mfer_0736
COGs: COG0717 Deoxycytidine deaminase; KEGG: mth:MTH1605 deoxycytidine-triphosphate deaminase related protein; SPTR: O27642 Probable deoxyuridine 5'-triphosphate nucleotidohydrolase; PFAM: dUTPase.
       0.536
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.510
cdhE
acetyl-CoA decarbonylase/synthase gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
    0.499
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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