STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0947COGs: COG2074 2-phosphoglycerate kinase; InterPro IPR004173; KEGG: mth:MTH1835 hypothetical protein; PFAM: 3H domain protein; SPTR: O27863 2-phosphoglycerate kinase homolog; PFAM: Zeta toxin; 3H domain. (325 aa)    
Predicted Functional Partners:
Mfer_0946
COGs: COG1779 C4-type Zn-finger protein; InterPro IPR004457: IPR004470; KEGG: mth:MTH1834 hypothetical protein; PFAM: ZPR1-type Zinc finger domain protein; SMART: ZPR1-type Zinc finger domain protein; SPTR: O27862 Conserved protein; TIGRFAM: ZPR1-related zinc finger protein; ZPR1-like zinc finger protein; PFAM: ZPR1 zinc-finger domain; TIGRFAM: ZPR1-related zinc finger protein; ZPR1 zinc finger domain.
       0.805
Mfer_0948
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: mth:MTH1836 hypothetical protein; PFAM: Roadblock/LC7 family protein; SPTR: O27864 Conserved protein; PFAM: Roadblock/LC7 domain.
       0.761
Mfer_0949
KEGG: MIR domain protein; SPTR: Q7RRW7 Putative uncharacterized protein PY00600 (Fragment).
       0.614
Mfer_0950
KEGG: conserved hypothetical protein; SPTR: Q8ILP9 Putative uncharacterized protein.
       0.614
Mfer_0304
Protein of unknown function DUF1611; COGs: COG3367 conserved hypothetical protein; InterPro IPR011669: IPR016040; KEGG: mth:MTH1837 hypothetical protein; PFAM: protein of unknown function DUF1611; SPTR: O27865 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1611).
 
     0.486
Mfer_0336
Mur ligase middle domain protein; COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR018109: IPR013221: IPR004101: IPR016040; KEGG: mth:MTH530 UDP-N-acetylmuramyl tripeptide synthetase related protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: O26630 UDP-N-acetylmuramyl tripeptide synthetase related protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain.
  
     0.434
Mfer_1049
COGs: COG4076 RNA methylase; KEGG: msi:Msm_0363 RNA methylase; SPTR: A5UK40 Predicted RNA methylase; PFAM: Ribosomal RNA adenine dimethylase.
  
     0.433
Mfer_0275
Oligosaccharyl transferase STT3 subunit; COGs: COG1287 membrane protein required for N-linked glycosylation; InterPro IPR003674; KEGG: mth:MTH1898 oligosaccharyl transferase; PFAM: Oligosaccharyl transferase STT3 subunit; SPTR: O27920 Oligosaccharyl transferase; PFAM: Oligosaccharyl transferase STT3 subunit.
  
     0.419
Mfer_0113
Pyridoxal phosphate enzyme; COGs: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; InterPro IPR015424: IPR018319: IPR020033; KEGG: msi:Msm_0767 selenocysteine synthase, SelA; PFAM: Pyridoxal phosphate-dependent transferase; SPTR: A5UL94 Selenocysteine synthase, SelA; TIGRFAM: pyridoxal phosphate enzyme; PFAM: L-seryl-tRNA selenium transferase; TIGRFAM: pyridoxal phosphate enzyme, MJ0158 family.
  
     0.405
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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