STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_1057COGs: COG2000 Fe-S protein; InterPro IPR007202; KEGG: mth:MTH1671 hypothetical protein; PFAM: Fe-S cluster domain protein; SPTR: O27707 Conserved protein; PFAM: Putative Fe-S cluster. (213 aa)    
Predicted Functional Partners:
Mfer_1058
Cobalamin synthesis protein P47K; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202: IPR003495; KEGG: mth:MTH1672 hypothetical protein; PFAM: cobalamin synthesis protein P47K; SPTR: O27708 Conserved protein; PFAM: CobW/HypB/UreG, nucleotide-binding domain.
  
    0.962
Mfer_1059
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: mth:MTH1673 sn-glycerol-3-phosphate transport ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: O27709 SN-glycerol-3-phosphate transport ATP-binding protein; PFAM: ABC transporter.
  
    0.962
Mfer_1060
Phosphosulfolactate synthase; COGs: COG1809 conserved hypothetical protein; InterPro IPR003830: IPR013785; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulfolactate synthase ComA; PRIAM: Phosphosulfolactate synthase; SPTR: O27710 Phosphosulfolactate synthase; PFAM: (2R)-phospho-3-sulfolactate synthase (ComA); TIGRFAM: phosphosulfolactate synthase.
  
    0.961
Mfer_1056
Protein of unknown function DUF129; COGs: COG4071 conserved hypothetical protein; InterPro IPR012030: IPR002847; KEGG: mth:MTH1670 hypothetical protein; PFAM: protein of unknown function DUF129; SPTR: O27706 Conserved protein; PFAM: F420-0:Gamma-glutamyl ligase.
       0.783
Mfer_1055
tRNA-archaeosine synthase; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478: IPR015947: IPR004521; KEGG: mth:MTH1665 hypothetical protein; PFAM: PUA domain containing protein; SMART: PUA domain containing protein; SPTR: O27701 Conserved protein; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2.
       0.773
Mfer_0402
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR012202: IPR004392: IPR003495; KEGG: mth:MTH782 hydrogenase expression/formation protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: O26875 Hydrogenase expression/formation protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: urease accessory protein UreG; hydrogenase accessory protein HypB.
  
    0.654
Mfer_1061
Glycoside hydrolase family 18; InterPro IPR017853: IPR013781: IPR001223; KEGG: msi:Msm_0219 cysteine protease; PFAM: glycoside hydrolase family 18; SPTR: A5UJP6 Putative cysteine protease (Transglutaminase-like superfamily); PFAM: Glycosyl hydrolases family 18.
       0.516
Mfer_1062
Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: msi:Msm_1208 teichoic acid transporter; PFAM: polysaccharide biosynthesis protein; SPTR: B9AFJ0 Putative uncharacterized protein; PFAM: Polysaccharide biosynthesis protein.
       0.457
map
Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
       0.448
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
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