STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_1219COGs: COG2016 RNA-binding protein (contains PUA domain); InterPro IPR016437: IPR002478: IPR015947: IPR004521; KEGG: mfe:Mefer_1390 PUA domain containing protein; PFAM: PUA domain containing protein; SMART: PUA domain containing protein; SPTR: C7P9G5 PUA domain containing protein; PFAM: Domain of unknown function (DUF1947); PUA domain; TIGRFAM: arCOG04150 universal archaeal PUA-domain protein; uncharacterized domain 2. (159 aa)    
Predicted Functional Partners:
arfB
Creatininase; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
       0.877
Mfer_1217
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
       0.865
rps28e
COGs: COG2053 Ribosomal protein S28E/S33; InterPro IPR016027: IPR000289: IPR012340; KEGG: msi:Msm_0205 30S ribosomal protein S28e; PFAM: Ribosomal protein S28e; SPTR: A5UJN2 Ribosomal protein S28e; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 
 
 0.863
rps2
COGs: COG0052 Ribosomal protein S2; InterPro IPR018130: IPR005707: IPR001865; KEGG: mth:MTH44 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: O26150 30S ribosomal protein S2P; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); Belongs to the universal ribosomal protein uS2 family.
  
 
 0.851
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 
 
 0.850
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
 
   0.844
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR018281: IPR001593; KEGG: mth:MTH1593 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: O27630 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
   0.842
rps24e
COGs: COG2004 Ribosomal protein S24E; InterPro IPR001976: IPR012677; KEGG: mth:MTH267 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; SPTR: O26367 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
   0.828
rps4e
COGs: COG1471 Ribosomal protein S4E; InterPro IPR018199: IPR000876: IPR013845: IPR002942: IPR 013843; KEGG: mth:MTH15 30S ribosomal protein S4e; PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: O26123 30S ribosomal protein S4e; PFAM: S4 domain; Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family.
    
 
 0.827
rps6e
COGs: COG2125 Ribosomal protein S6E (S10); InterPro IPR018282: IPR001377; KEGG: mth:MTH260 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; SPTR: O26360 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 
 0.817
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.