close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_1237KEGG: mth:MTH1181 hypothetical protein; SPTR: O27249 Putative uncharacterized protein. (175 aa)    
Predicted Functional Partners:
Mfer_1238
Methanogenesis marker protein 7; COGs: COG4052 Uncharacterized protein related to methyl coenzyme M reductase subunit C; InterPro IPR011312; KEGG: mth:MTH1180 hypothetical protein; PFAM: Protein of unknown function UCP019164; SPTR: O27248 Conserved protein; TIGRFAM: methanogenesis marker protein 7; PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: putative methanogenesis marker protein 7.
       0.883
Mfer_1239
TraB determinant protein; COGs: COG1916 Uncharacterized homolog of PrgY (pheromone shutdown protein); InterPro IPR002816; KEGG: mth:MTH1183 pheromone shutdown protein TraB; PFAM: TraB determinant protein; SPTR: O27251 Pheromone shutdown protein TraB; PFAM: TraB family; TIGRFAM: pheromone shutdown-related protein TraB.
       0.796
Mfer_1240
Domain of unknown function DUF1922; InterPro IPR015166; KEGG: mth:MTH1184 hypothetical protein; PFAM: Domain of unknown function DUF1922; SPTR: O27252 Protein MTH_1184; PFAM: Domain of unknown function (DUF1922).
       0.789
Mfer_1241
Translation elongation factor 1A GTP binding domain family; COGs: COG5258 GTPase; InterPro IPR009000: IPR009001: IPR000795: IPR004161: IPR 004160; KEGG: mth:MTH1185 translation elongation factor, EF-1 alpha related protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain protein; SPTR: O27253 Translation elongation factor, EF-1 alpha related protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: translation elongation factor TU.
       0.781
Mfer_1236
2-phosphosulfolactate phosphatase; COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: msi:Msm_1023 2-phosphosulpholactate phosphatase, ComB, (coenzyme M biosynthesis); PFAM: 2-phosphosulfolactate phosphatase; PRIAM: 2-phosphosulfolactate phosphatase; SPTR: A5UM00 2-phosphosulpholactate phosphatase, ComB, (Coenzyme M biosynthesis); TIGRFAM: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase.
       0.615
Mfer_1235
ThiJ/PfpI domain protein; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818; KEGG: mmz:MmarC7_1578 PfpI family intracellular peptidase; PFAM: ThiJ/PfpI domain protein; SPTR: A6VJL0 Intracellular protease, PfpI family; PFAM: DJ-1/PfpI family.
       0.434
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
Server load: low (26%) [HD]