STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiAGlucose-6-phosphate isomerase; Catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the archaeal-type GPI family. (190 aa)    
Predicted Functional Partners:
glkA
ADP-dependent glucokinase; Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate. Can also use CDP as the phosphoryl group donor and D-1,5-anhydroglucitol as the phosphoryl group acceptor.
    
 0.946
OCC_09933
Iron-sulfur cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
  0.944
pfkC
Phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
    
 0.924
OCC_03567
Sugar kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.919
cpsB
Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.918
OCC_09676
Bifunctional phosphomannomutase/phosphoglucomutase; Catalyzes the interconversion of alpha-D-mannose 1-phosphate to alpha-D-mannose 6-phosphate and alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.917
OCC_05576
Transketolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
  0.915
OCC_05571
Transketolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
  0.912
fbp
Fructose-1 6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.907
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
  0.901
Your Current Organism:
Thermococcus litoralis
NCBI taxonomy Id: 523849
Other names: T. litoralis DSM 5473, Thermococcus litoralis ATCC 51850, Thermococcus litoralis DSM 5473, Thermococcus litoralis JCM 8560, Thermococcus litoralis NS-C, Thermococcus litoralis str. DSM 5473, Thermococcus litoralis strain DSM 5473
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.