STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (224 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.999
pgk
Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phosphoglycerate kinase family.
 
 
 0.996
fbp
Fructose-1 6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.984
OCC_09591
Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.974
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.972
gpmA
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.971
OCC_00992
Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.969
OCC_05826
Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.967
OCC_03612
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.946
OCC_12546
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family.
  
 0.936
Your Current Organism:
Thermococcus litoralis
NCBI taxonomy Id: 523849
Other names: T. litoralis DSM 5473, Thermococcus litoralis ATCC 51850, Thermococcus litoralis DSM 5473, Thermococcus litoralis JCM 8560, Thermococcus litoralis NS-C, Thermococcus litoralis str. DSM 5473, Thermococcus litoralis strain DSM 5473
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