Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TON_0002Predicted Hydrolase; HAD superfamily. (231 aa)    
Predicted Functional Partners:
TON_0004
Hypothetical membrane protein, conserved; Similar to Thermococcus kodakarensis KOD1 protein AF0802.
     
 0.889
TON_0003
Conserved hypothetical protein; Similar to Thermococcus kodakarensis KOD1 protein PH0156.
       0.886
TON_0005
S-layer protein precursor; Similar to Thermococcus kodakarensis KOD1 protein PAB1861.
       0.700
TON_0008
Hypothetical protein, conserved.
       0.664
TON_0335
Arginase; Belongs to the arginase family.
  
  
 0.658
hisC
Hypothetical histidinol-phosphate aminotransferase.
  
  
 0.639
dcd
dUTPase; Catalyzes the deamination of dCTP to dUTP.
  
  
 0.636
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.630
TON_0218
Subunit A' of DNA-dependent RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.622
TON_1705
Protein involved in mitomycin biosynthesis.
      
 0.618
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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