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psmA protein (Thermococcus onnurineus) - STRING interaction network
"psmA" - Proteasome subunit alpha in Thermococcus onnurineus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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psmAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (260 aa)    
Predicted Functional Partners:
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (398 aa)
   
  0.997
psmB1
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (203 aa)
 
 
0.995
TON_1119
Metalloprotease (148 aa)
     
  0.988
TON_0526
Metalloprotease (123 aa)
     
  0.988
psmB2
Proteasome subunit beta 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (200 aa)
 
 
0.968
TON_0028
Putative RNA-associated protein (236 aa)
 
        0.961
rrp42
Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site (272 aa)
 
 
  0.936
rrp41
Exosome complex exonuclease Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3’->5’ exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (249 aa)
   
 
  0.932
rrp4
Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (256 aa)
 
   
  0.927
TON_1094
CDC48/VCP (838 aa)
 
 
  0.922
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus, T. onnurineus NA1, Thermococcus onnurineus, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1, Thermococcus sp. NA1
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