Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
hypAhypA hydrogenase expression/formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (139 aa)    
Predicted Functional Partners:
TON_0262
ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
 
   0.991
TON_0263
Hydrogenase maturation protease HycI.
 
  
 0.950
TON_1559
(8-hydroxy-5-deazaflavin-reducing hydrogenase alpha subunit) (FRH).
 
 
 0.950
TON_0052
H-II alpha (hydrogenase subunit alpha).
 
 
 0.920
TON_0534
Cytosolic NiFe-hydrogenase, alpha subunit.
 
 
 0.919
TON_0286
Hydrogenase maturation protein HypF.
 
   
 0.861
TON_1569
Hydrogenase 4, component G or formate hydrogen lyase, subunit 5.
 
 
 0.847
TON_0287
Hydrogenase expression/formation protein HypE.
 
  
 0.798
TON_0283
hypC hydrogenase expression/formation protein.
 
  
 0.746
TON_0260
Cobalt/zinc/cadmium cation efflux pump protein.
     
 0.739
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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