STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.959
guaAB
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.951
rps2
SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.938
dcd
dUTPase; Catalyzes the deamination of dCTP to dUTP.
  
 
 0.930
TON_1870
nrdD anaerobic ribonucleoside triphosphate reductase.
  
  
 0.924
rpl13
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.898
TON_0217
Subunit B of DNA-dependent RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.898
argS
arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.895
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.870
rpl1
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
 
 0.867
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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