STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdhThreonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (350 aa)    
Predicted Functional Partners:
TON_1415
2-amino-3-oxobutyrate coenzyme A ligase.
 
 
 0.977
TON_0166
Pyridoxal phosphate dependent enzyme.
  
 
 0.905
TON_1232
Hypothetical threonine synthase (TS); Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 
 0.905
TON_1428
Threonine synthase.
   
 
 0.905
TON_0443
Oxidoreductase; Aldo/keto reductase family.
  
 
 0.673
pheS
phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
     
 0.655
pheT
phenylalanyl-tRNA synthetase, beta subunit.
       0.627
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
  
 0.599
TON_0398
ATPase; Involved in chromosome partitioning, ParA/MinD family.
       0.596
TON_0399
3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
     
 0.591
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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