node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TON_0366 | TON_0663 | TON_0366 | TON_0663 | Adenylate cyclase, class 2. | Adenylate cyclase; Class 2. | 0.917 |
TON_0366 | TON_0785 | TON_0366 | TON_0785 | Adenylate cyclase, class 2. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.900 |
TON_0366 | TON_0933 | TON_0366 | TON_0933 | Adenylate cyclase, class 2. | Hypothetical ATPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.912 |
TON_0366 | TON_1870 | TON_0366 | TON_1870 | Adenylate cyclase, class 2. | nrdD anaerobic ribonucleoside triphosphate reductase. | 0.900 |
TON_0366 | dacZ | TON_0366 | TON_0660 | Adenylate cyclase, class 2. | Hypothetical protein, conserved; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.507 |
TON_0366 | moaA | TON_0366 | TON_1410 | Adenylate cyclase, class 2. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.809 |
TON_0366 | mptA | TON_0366 | TON_0757 | Adenylate cyclase, class 2. | Hypothetical protein, conserved; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.800 |
TON_0366 | ndk | TON_0366 | TON_0951 | Adenylate cyclase, class 2. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.914 |
TON_0366 | ribA | TON_0366 | TON_0608 | Adenylate cyclase, class 2. | Riboflavin biosynthesis protein RibD; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.800 |
TON_0662 | TON_0663 | TON_0662 | TON_0663 | Hypothetical transcription regulator; Lrp/AsnC family. | Adenylate cyclase; Class 2. | 0.830 |
TON_0662 | dacZ | TON_0662 | TON_0660 | Hypothetical transcription regulator; Lrp/AsnC family. | Hypothetical protein, conserved; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.548 |
TON_0663 | TON_0366 | TON_0663 | TON_0366 | Adenylate cyclase; Class 2. | Adenylate cyclase, class 2. | 0.917 |
TON_0663 | TON_0662 | TON_0663 | TON_0662 | Adenylate cyclase; Class 2. | Hypothetical transcription regulator; Lrp/AsnC family. | 0.830 |
TON_0663 | TON_0785 | TON_0663 | TON_0785 | Adenylate cyclase; Class 2. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.900 |
TON_0663 | TON_0933 | TON_0663 | TON_0933 | Adenylate cyclase; Class 2. | Hypothetical ATPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.900 |
TON_0663 | TON_1870 | TON_0663 | TON_1870 | Adenylate cyclase; Class 2. | nrdD anaerobic ribonucleoside triphosphate reductase. | 0.900 |
TON_0663 | dacZ | TON_0663 | TON_0660 | Adenylate cyclase; Class 2. | Hypothetical protein, conserved; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.719 |
TON_0663 | moaA | TON_0663 | TON_1410 | Adenylate cyclase; Class 2. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.809 |
TON_0663 | mptA | TON_0663 | TON_0757 | Adenylate cyclase; Class 2. | Hypothetical protein, conserved; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.800 |
TON_0663 | ndk | TON_0663 | TON_0951 | Adenylate cyclase; Class 2. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.913 |