Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TON_0680Uracil-DNA glycosylase. (248 aa)    
Predicted Functional Partners:
TON_1518
Uracil-DNA glycosylase.
  
  
 
0.921
TON_0678
hisC histidinol-phosphate aminotransferase.
  
    0.919
cobD
Cobinamide synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.918
TON_0683
Hypothetical protein, conserved; DUF64 family.
  
    0.871
cobS
cobS cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
  
 0.861
TON_0682
Hypothetical ATPase; PP-loop superfamily, similar to hypothetical protein PH0375 of Pyrococcus horikoshii OT3.
       0.854
TON_0681
Hypothetical protein.
       0.802
TON_1972
SAM-dependent methyltransferase; UbiE/COQ5 family.
       0.612
TON_0389
Hypothetical protein, conserved; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates.
      
 0.524
TON_0157
Glutamate dehydrogenase (GDH); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.491
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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