Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TON_0697Hypothetical transcription regulator; Containing DNA-binding HTH domain. (319 aa)    
Predicted Functional Partners:
tiaS
Nucleic acid-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.834
TON_0955
Hypothetical protein, conserved.
  
     0.628
TON_0589
Hypothetical protein, conserved; Radical SAM superfamily.
  
     0.624
TON_1505
RNA-binding protein; Containing PUA domain.
  
     0.614
trmY
Hypothetical protein, conserved; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
  
     0.605
TON_0698
N-acetyltransferase; GNAT family.
       0.599
TON_1048
Hypothetical protein, conserved; UPF0179 family; Belongs to the UPF0179 family.
  
     0.595
TON_1504
Hypothetical protein, conserved.
 
     0.560
TON_1489
Hypothetical protein, conserved.
 
     0.556
carS
Hypothetical membrane protein, conserved; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.551
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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