Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TON_0804Zinc-dependent protease; TldD/PmbA family. (473 aa)    
Predicted Functional Partners:
TON_0805
Zinc-dependent protease; TldD/PmbA family.
 
   
0.940
TON_0672
Zinc-dependent protease; TldD/PmbA family.
 
   
 0.766
TON_0803
Hypothetical permease; Major facilitator superfamily.
       0.535
TON_0111
Enolase-related protein.
   
 
 0.488
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.488
TON_0806
Hypothetical membrane protein, conserved.
       0.413
TON_1453
Zinc-dependent protease; TldD/PmbA family.
 
   
0.410
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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