Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TON_0806Hypothetical membrane protein, conserved. (202 aa)    
Predicted Functional Partners:
TON_0807
Hypothetical protein.
       0.714
TON_1933
Hypothetical protein, conserved; DUF74 family; Belongs to the UPF0145 family.
       0.586
TON_1932
Hypothetical membrane protein, conserved.
       0.518
TON_1934
Diphthine synthase, DPH2 subunit; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
       0.475
pyrB
Aspartate carbamoyltransferase, catalytic subunit.
      
 0.468
TON_0805
Zinc-dependent protease; TldD/PmbA family.
       0.420
TON_0804
Zinc-dependent protease; TldD/PmbA family.
       0.413
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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