node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TON_0001 | TON_0043 | TON_0001 | TON_0043 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | 0.980 |
TON_0001 | fen | TON_0001 | TON_1099 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.981 |
TON_0001 | lig | TON_0001 | TON_1515 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | Thermostable DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can use both ATP and NAD(+), but NAD(+) may be a preferred nucleotide cofactor. | 0.887 |
TON_0001 | pcn | TON_0001 | TON_0826 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | Proliferating cell nuclear antigen (PCNA); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.999 |
TON_0001 | polB | TON_0001 | TON_1643 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | DNA polymerase II, small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.999 |
TON_0001 | polC | TON_0001 | TON_1642 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | DNA polymerase II, small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.643 |
TON_0001 | priL | TON_0001 | TON_1778 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | Eukaryotic-type DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.999 |
TON_0001 | priS | TON_0001 | TON_1777 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | Eukaryotic-type DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after p [...] | 0.999 |
TON_0001 | rfcS | TON_0001 | TON_1414 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | ATPase involved in DNA replication; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.850 |
TON_0001 | rpl40e | TON_0001 | TON_0113 | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.903 |
TON_0043 | TON_0001 | TON_0043 | TON_0001 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B). | 0.980 |
TON_0043 | fen | TON_0043 | TON_1099 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.811 |
TON_0043 | lig | TON_0043 | TON_1515 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | Thermostable DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can use both ATP and NAD(+), but NAD(+) may be a preferred nucleotide cofactor. | 0.604 |
TON_0043 | pcn | TON_0043 | TON_0826 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | Proliferating cell nuclear antigen (PCNA); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.961 |
TON_0043 | polB | TON_0043 | TON_1643 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | DNA polymerase II, small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.551 |
TON_0043 | polC | TON_0043 | TON_1642 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | DNA polymerase II, small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.651 |
TON_0043 | priL | TON_0043 | TON_1778 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | Eukaryotic-type DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.976 |
TON_0043 | priS | TON_0043 | TON_1777 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | Eukaryotic-type DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after p [...] | 0.941 |
TON_0043 | rfcS | TON_0043 | TON_1414 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | ATPase involved in DNA replication; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.904 |
TON_0043 | rpl40e | TON_0043 | TON_0113 | Hypothetical cell division control protein; Similar to protein PAB2373-1 of Pyrococcus horikoshii OT3. | LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.683 |