Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TON_0840Copper-transporting ATPase; P-type (copB). (642 aa)    
Predicted Functional Partners:
TON_0855
NAD(P)H oxidase.
  
  
 0.663
TON_1772
glnA glutamine synthetase.
     
 0.645
TON_0538
Hypothetical formate transporter.
  
  
 0.632
TON_1573
Hypothetical formate transporter.
  
  
 0.632
TON_0486
Membrane bound hydrogenase; 4Fe-4S cluster-binding subunit.
     
 0.628
pcn
Proliferating cell nuclear antigen (PCNA); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
     
 0.628
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase.
     
 0.627
albA
Archaeal chromatin protein, Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
   
  
 0.627
TON_0783
Cationic amino acid transporter (cat-1).
     
 0.620
TON_0903
Fructose-1,6-bisphosphate aldolase.
     
 0.619
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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