| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TON_0785 | TON_0903 | TON_0785 | TON_0903 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Fructose-1,6-bisphosphate aldolase. | 0.906 |
| TON_0785 | TON_1131 | TON_0785 | TON_1131 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Transketolase, N-terminal section. | 0.824 |
| TON_0785 | TON_1527 | TON_0785 | TON_1527 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Fuculose-1-phosphate aldolase. | 0.550 |
| TON_0785 | deoC | TON_0785 | TON_1608 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.826 |
| TON_0785 | eno | TON_0785 | TON_1613 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.995 |
| TON_0785 | fbp | TON_0785 | TON_1497 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Thermophile-specific fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) (By similarity). Can also dephosphorylate, with lower activity, other related substrates including fructose-1-phosphate, fructose-6-phosphate, glucose-1- phosphate, glucose-6-phosphate, glycerol-2-phosphate, phosphoenolpyruvate, 5'-AMP, 6'-ADP and 7'-ATP. | 0.915 |
| TON_0785 | gap | TON_0785 | TON_0639 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.978 |
| TON_0785 | glkA | TON_0785 | TON_0246 | Pyruvate kinase; Belongs to the pyruvate kinase family. | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. | 0.597 |
| TON_0785 | pfkC | TON_0785 | TON_1012 | Pyruvate kinase; Belongs to the pyruvate kinase family. | ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. | 0.841 |
| TON_0785 | tpiA | TON_0785 | TON_1640 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.948 |
| TON_0903 | TON_0785 | TON_0903 | TON_0785 | Fructose-1,6-bisphosphate aldolase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.906 |
| TON_0903 | TON_1131 | TON_0903 | TON_1131 | Fructose-1,6-bisphosphate aldolase. | Transketolase, N-terminal section. | 0.905 |
| TON_0903 | TON_1527 | TON_0903 | TON_1527 | Fructose-1,6-bisphosphate aldolase. | Fuculose-1-phosphate aldolase. | 0.921 |
| TON_0903 | deoC | TON_0903 | TON_1608 | Fructose-1,6-bisphosphate aldolase. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.915 |
| TON_0903 | eno | TON_0903 | TON_1613 | Fructose-1,6-bisphosphate aldolase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.913 |
| TON_0903 | fbp | TON_0903 | TON_1497 | Fructose-1,6-bisphosphate aldolase. | Thermophile-specific fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) (By similarity). Can also dephosphorylate, with lower activity, other related substrates including fructose-1-phosphate, fructose-6-phosphate, glucose-1- phosphate, glucose-6-phosphate, glycerol-2-phosphate, phosphoenolpyruvate, 5'-AMP, 6'-ADP and 7'-ATP. | 0.950 |
| TON_0903 | gap | TON_0903 | TON_0639 | Fructose-1,6-bisphosphate aldolase. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.963 |
| TON_0903 | glkA | TON_0903 | TON_0246 | Fructose-1,6-bisphosphate aldolase. | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. | 0.944 |
| TON_0903 | pfkC | TON_0903 | TON_1012 | Fructose-1,6-bisphosphate aldolase. | ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. | 0.950 |
| TON_0903 | tpiA | TON_0903 | TON_1640 | Fructose-1,6-bisphosphate aldolase. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.969 |