Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TON_0922Short-chain alcohol dehydrogenase, N-terminus. (34 aa)    
Predicted Functional Partners:
TON_1302
Hypothetical acetyl CoA acetyl transferase; Nonspecific lipid-transfer protein similar to protein PH0676 of Pyrococcus horikoshii OT3.
  
 
 0.625
mre11
DNA repair exonuclease; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
  
 
 0.579
TON_0923
Short-chain alcohol dehydrogenase, C-terminus.
       0.568
TON_0487
nuoD NADH dehydrogenase I, subunit D; Belongs to the complex I 49 kDa subunit family.
  
 
 0.544
TON_0921
Iron-molybdenum cofactor-binding protein.
       0.509
TON_1303
Hypothetical protein, conserved; DUF35 family.
   
 
 0.458
TON_0489
nuoB NADH dehydrogenase I, subunit B; Belongs to the complex I 20 kDa subunit family.
  
 
 0.432
TON_0920
Hypothetical protein, conserved.
       0.408
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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