Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TON_1102Double-stranded DNA-binding protein; Belongs to the PDCD5 family. (112 aa)    
Predicted Functional Partners:
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
 
    0.989
TON_1105
Hypothetical ATPase; PP-loop superfamily.
  
    0.958
TON_1101
Hypothetical protein.
       0.907
rps28e
SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family.
 
    0.896
rpl30e
Ribosomal protein 30; Belongs to the eukaryotic ribosomal protein eL30 family.
  
    0.888
TON_1104
Hypothetical RNA-binding protein; CRS1/YhbY family.
 
     0.882
tfb
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
       0.880
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
    0.877
rpl14e
LSU ribosomal protein L14E; Belongs to the eukaryotic ribosomal protein eL14 family.
  
    0.876
nusA
Transcription termination-antitermination factor; Participates in transcription termination. Belongs to the NusA family.
  
    0.876
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.