Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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eif6Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (228 aa)    
Predicted Functional Partners:
rpl18a
LSU ribosomal protein L20A.
 
 
 0.996
rpl31e
LSU ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.995
rpl3
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.974
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.963
rpl30e
Ribosomal protein 30; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 
 0.957
rpl34e
LSU ribosomal protein L34E; Belongs to the eukaryotic ribosomal protein eL34 family.
 
 
 0.946
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.935
rpl24
LSU ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit.
 
 
 0.929
rpl24e
LSU ribosomal protein L24E; Binds to the 23S rRNA.
 
 
 0.929
rpl39e
LSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family.
  
  
 0.914
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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