Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TON_1600Hypothetical ATPase; AAA superfamily. (401 aa)    
Predicted Functional Partners:
TON_1599
RNA-binding protein; Containing THUMP domain.
 
     0.933
TON_1601
Hypothetical membrane-bound metal-dependent hydrolase.
     
 0.919
TON_1602
Similar to protein PH1685 of Pyrococcus horikoshii OT3.
       0.841
TON_1603
Thioredoxin reductase.
     
 0.758
TON_1627
Similar to protein PH0286 of Pyrococcus horikoshii OT3.
  
     0.685
TON_1315
Hypothetical transcription regulator; Containing cell wall binding repeat 2 and DNA-binding HTH domains.
  
     0.683
TON_1954
Replication factor A complex, RPA41 subunit.
  
     0.675
TON_1545
Hypothetical protein, conserved.
  
     0.665
TON_1605
Aminotransferase; Class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.634
TON_0453
Component of the U3 small nucleolar ribonucleoprotein; Probably involved in the biogenesis of the ribosome.
  
     0.621
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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