Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TON_1966tRNA/rRNA cytosine-C5-methylase; NOL1/NOP2/Sun family, fused to N-terminal NusB regulator domain; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa)    
Predicted Functional Partners:
TON_0001
Family B-type DNA-dependent polymerase precursor; DNA polymerase elongation subunit (family B).
  
  
 0.726
TON_1299
snoRNP component; Nop56p/58p-like protein.
   
 
 0.718
TON_1672
GTPase; MMR1/HSR1 family.
 
 
 0.693
TON_1737
Hypothetical protein, conserved; UPF0113 family.
  
 
 0.678
TON_0356
Predicted GTPase; Containing NOG1 domain.
   
 
 0.659
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.609
rps8e
SSU ribosomal protein S8E.
   
 
 0.609
rpl30
LSU ribosomal protein L30P.
   
 
 0.599
TON_0453
Component of the U3 small nucleolar ribonucleoprotein; Probably involved in the biogenesis of the ribosome.
   
 
 0.594
tmcA
Hypothetical ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 
 0.590
Your Current Organism:
Thermococcus onnurineus
NCBI taxonomy Id: 523850
Other names: T. onnurineus NA1, Thermococcus onnurineus NA1, Thermococcus onnurineus str. NA1, Thermococcus onnurineus strain NA1
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