Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ddes_0200PFAM: PfkB domain protein; KEGG: dvl:Dvul_2001 ribokinase-like domain-containing protein. (318 aa)    
Predicted Functional Partners:
Ddes_0095
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dvl:Dvul_0426 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.940
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.921
Ddes_0461
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.918
Ddes_1511
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cpr:CPR_1917 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein; Belongs to the 5'-nucleotidase family.
  
 
 0.910
Ddes_0550
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: dvl:Dvul_1871 nucleoside triphosphate pyrophosphohydrolase.
    
  0.906
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
  0.904
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Ddes_0794
PFAM: protein of unknown function DUF152; KEGG: dvl:Dvul_2619 hypothetical protein.
     
  0.900
Ddes_1875
PFAM: Hpt domain protein; KEGG: pmy:Pmen_0835 multi-sensor hybrid histidine kinase.
  
  
 0.763
hisA
KEGG: dvl:Dvul_1955 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein.
  
    0.728
Your Current Organism:
Desulfovibrio desulfuricans ATCC 27774
NCBI taxonomy Id: 525146
Other names: D. desulfuricans ATCC 27774, Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
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