Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
Ddes_1985KEGG: dvu:DVU2490 histidinol phosphatase, putative; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; Belongs to the PHP hydrolase family. HisK subfamily. (275 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.924
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_1964 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.914
Ddes_0366
TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: dvu:DVU2490 histidinol phosphatase, putative; Belongs to the PHP hydrolase family. HisK subfamily.
  
  
 
0.913
Ddes_1683
PFAM: inositol monophosphatase; KEGG: smd:Smed_5476 histidinol-phosphate phosphatase, putative.
     
  0.900
Ddes_1986
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dvu:DVU2491 ABC transporter, ATP-binding protein.
  
    0.555
Ddes_2120
Putative signal transduction protein with EFhand domain; PFAM: Calcium-binding EF-hand-containing protein; KEGG: dvl:Dvul_0821 calcium-binding EF-hand-containing protein.
  
     0.490
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
 
  
 0.477
Ddes_1556
PFAM: protein of unknown function UPF0054; KEGG: dvl:Dvul_1281 hypothetical protein.
   
    0.435
Ddes_0949
KEGG: dvl:Dvul_1729 putative lipoprotein.
  
     0.431
Ddes_1983
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dvl:Dvul_0767 ferredoxin--NADP(+) reductase subunit alpha.
  
    0.426
Your Current Organism:
Desulfovibrio desulfuricans ATCC 27774
NCBI taxonomy Id: 525146
Other names: D. desulfuricans ATCC 27774, Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
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