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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: dvl:Dvul_0218 glutamate-1-semialdehyde-2,1-aminomutase. (423 aa)    
Predicted Functional Partners:
Ddes_0288
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: dvu:DVU0856 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.992
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.989
Ddes_1336
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: hau:Haur_3962 beta-ketoacyl synthase.
 
  
 0.927
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.926
Ddes_1335
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein.
  
 
 0.903
Ddes_2207
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dvl:Dvul_2236 uroporphyrin-III C-methyltransferase.
 
  
 0.829
Ddes_1337
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein.
  
 
 0.745
Ddes_2061
PFAM: Acyl transferase; KEGG: sco:SCO5892 polyketide synthase.
  
  
 0.701
Ddes_2014
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: dvu:DVU3170 precorrin-3b C17-methyltransferase.
     
 0.636
Ddes_2015
PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: dvl:Dvul_0217 cobalamin (vitamin B12) biosynthesis CbiG protein.
     
 0.596
Your Current Organism:
Desulfovibrio desulfuricans ATCC 27774
NCBI taxonomy Id: 525146
Other names: D. desulfuricans ATCC 27774, Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
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