STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEH64372.1Glycine radical domain protein; COG: COG1882; Pfam: PF01228; InterPro: IPR001150. (121 aa)    
Predicted Functional Partners:
pflB
Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR005949.
  
  0.999
pflA
Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.970
EEH63196.1
Malic enzyme, NAD binding domain protein; COG: COG0281; Pfam: PF00390,PF03949; InterPro: IPR016040.
   
 
 0.941
pta
Phosphate acetyltransferase; COG: COG0280; Pfam: PF01515; InterPro: IPR002505.
   
 
 0.937
pyk
Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family.
   
 
 0.935
ilvB
Acetolactate synthase, large subunit, biosynthetic type; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012846.
     
 0.934
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.934
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 
 0.932
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.932
ppdK
Pyruvate, phosphate dikinase; COG: COG0574; Pfam: PF01326,PF00391,PF02896; InterPro: IPR010121; Belongs to the PEP-utilizing enzyme family.
    
 0.931
Your Current Organism:
Gleimia coleocanis
NCBI taxonomy Id: 525245
Other names: Actinomyces coleocanis DSM 15436, Actinomyces coleocanis str. DSM 15436, Actinomyces coleocanis strain DSM 15436, G. coleocanis DSM 15436, Gleimia coleocanis DSM 15436
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