node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEH64238.1 | EEH64239.1 | HMPREF0044_0527 | HMPREF0044_0528 | Hypothetical protein. | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | 0.897 |
EEH64238.1 | EEH64240.1 | HMPREF0044_0527 | HMPREF0044_0529 | Hypothetical protein. | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | 0.791 |
EEH64238.1 | EEH64242.1 | HMPREF0044_0527 | HMPREF0044_0531 | Hypothetical protein. | Hypothetical protein; COG: COG3599. | 0.735 |
EEH64238.1 | coaD | HMPREF0044_0527 | HMPREF0044_0530 | Hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.791 |
EEH64238.1 | mutM | HMPREF0044_0527 | HMPREF0044_0534 | Hypothetical protein. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.614 |
EEH64238.1 | rpmB | HMPREF0044_0527 | HMPREF0044_0526 | Hypothetical protein. | Ribosomal protein L28; Pfam: PF00830; InterPro: IPR001383; Belongs to the bacterial ribosomal protein bL28 family. | 0.619 |
EEH64239.1 | EEH64238.1 | HMPREF0044_0528 | HMPREF0044_0527 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | Hypothetical protein. | 0.897 |
EEH64239.1 | EEH64240.1 | HMPREF0044_0528 | HMPREF0044_0529 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | 0.798 |
EEH64239.1 | EEH64242.1 | HMPREF0044_0528 | HMPREF0044_0531 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | Hypothetical protein; COG: COG3599. | 0.735 |
EEH64239.1 | coaD | HMPREF0044_0528 | HMPREF0044_0530 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.823 |
EEH64239.1 | mutM | HMPREF0044_0528 | HMPREF0044_0534 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.742 |
EEH64239.1 | polA | HMPREF0044_0528 | HMPREF0044_1109 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.626 |
EEH64239.1 | recA | HMPREF0044_0528 | HMPREF0044_1021 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.794 |
EEH64239.1 | rpmB | HMPREF0044_0528 | HMPREF0044_0526 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | Ribosomal protein L28; Pfam: PF00830; InterPro: IPR001383; Belongs to the bacterial ribosomal protein bL28 family. | 0.632 |
EEH64239.1 | ruvA | HMPREF0044_0528 | HMPREF0044_1343 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.639 |
EEH64239.1 | topA | HMPREF0044_0528 | HMPREF0044_1522 | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.614 |
EEH64240.1 | EEH64238.1 | HMPREF0044_0529 | HMPREF0044_0527 | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | Hypothetical protein. | 0.791 |
EEH64240.1 | EEH64239.1 | HMPREF0044_0529 | HMPREF0044_0528 | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | Putative ATP-dependent DNA helicase RecG; COG: COG1200; Pfam: PF01336,PF00270,PF00271; InterPro: IPR014001. | 0.798 |
EEH64240.1 | EEH64242.1 | HMPREF0044_0529 | HMPREF0044_0531 | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | Hypothetical protein; COG: COG3599. | 0.765 |
EEH64240.1 | coaD | HMPREF0044_0529 | HMPREF0044_0530 | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.966 |