node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEH64031.1 | EEH64467.1 | HMPREF0044_1050 | HMPREF0044_0204 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | 0.711 |
EEH64031.1 | eno | HMPREF0044_1050 | HMPREF0044_0610 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.721 |
EEH64031.1 | fbaA | HMPREF0044_1050 | HMPREF0044_0190 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.711 |
EEH64031.1 | gpmA | HMPREF0044_1050 | HMPREF0044_1475 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.766 |
EEH64031.1 | pgi | HMPREF0044_1050 | HMPREF0044_0593 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.753 |
EEH64031.1 | pgk | HMPREF0044_1050 | HMPREF0044_1256 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.803 |
EEH64031.1 | tdh | HMPREF0044_1050 | HMPREF0044_1410 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.707 |
EEH64031.1 | tkt | HMPREF0044_1050 | HMPREF0044_1264 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.722 |
EEH64031.1 | tpiA | HMPREF0044_1050 | HMPREF0044_1257 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.802 |
EEH64031.1 | zwf | HMPREF0044_1050 | HMPREF0044_1262 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.726 |
EEH64467.1 | EEH64031.1 | HMPREF0044_0204 | HMPREF0044_1050 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078. | 0.711 |
EEH64467.1 | eno | HMPREF0044_0204 | HMPREF0044_0610 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.982 |
EEH64467.1 | fbaA | HMPREF0044_0204 | HMPREF0044_0190 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.944 |
EEH64467.1 | gpmA | HMPREF0044_0204 | HMPREF0044_1475 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.959 |
EEH64467.1 | pgi | HMPREF0044_0204 | HMPREF0044_0593 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.970 |
EEH64467.1 | pgk | HMPREF0044_0204 | HMPREF0044_1256 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.974 |
EEH64467.1 | tdh | HMPREF0044_0204 | HMPREF0044_1410 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.868 |
EEH64467.1 | tkt | HMPREF0044_0204 | HMPREF0044_1264 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.957 |
EEH64467.1 | tpiA | HMPREF0044_0204 | HMPREF0044_1257 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.982 |
EEH64467.1 | zwf | HMPREF0044_0204 | HMPREF0044_1262 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.896 |