node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEH63402.1 | EEH64331.1 | HMPREF0044_1326 | HMPREF0044_0068 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | 0.853 |
EEH63402.1 | EEH64473.1 | HMPREF0044_1326 | HMPREF0044_0210 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | 0.989 |
EEH63402.1 | adk | HMPREF0044_1326 | HMPREF0044_0420 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.853 |
EEH63402.1 | cdd | HMPREF0044_1326 | HMPREF0044_0747 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.864 |
EEH63402.1 | gmk | HMPREF0044_1326 | HMPREF0044_1299 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.856 |
EEH63402.1 | guaA | HMPREF0044_1326 | HMPREF0044_0719 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.879 |
EEH63402.1 | pdp | HMPREF0044_1326 | HMPREF0044_0748 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Pyrimidine-nucleoside phosphorylase; COG: COG0213; Pfam: PF02885,PF00591,PF07831; InterPro: IPR000053. | 0.864 |
EEH63402.1 | purH | HMPREF0044_1326 | HMPREF0044_0589 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695. | 0.858 |
EEH63402.1 | tdk | HMPREF0044_1326 | HMPREF0044_1071 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Thymidine kinase; COG: COG1435; Pfam: PF00265; InterPro: IPR001267. | 0.879 |
EEH63402.1 | upp | HMPREF0044_1326 | HMPREF0044_1517 | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.855 |
EEH64331.1 | EEH63402.1 | HMPREF0044_0068 | HMPREF0044_1326 | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | 0.853 |
EEH64331.1 | EEH64473.1 | HMPREF0044_0068 | HMPREF0044_0210 | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | 0.876 |
EEH64331.1 | gmk | HMPREF0044_0068 | HMPREF0044_1299 | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.933 |
EEH64331.1 | guaA | HMPREF0044_0068 | HMPREF0044_0719 | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.930 |
EEH64331.1 | purH | HMPREF0044_0068 | HMPREF0044_0589 | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695. | 0.427 |
EEH64473.1 | EEH63402.1 | HMPREF0044_0210 | HMPREF0044_1326 | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | LPXTG-motif cell wall anchor domain protein; COG: COG2374; Pfam: PF03372,PF00746; InterPro: IPR005135. | 0.989 |
EEH64473.1 | EEH64331.1 | HMPREF0044_0210 | HMPREF0044_0068 | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | Class I glutamine amidotransferase; Pfam: PF00117; InterPro: IPR000991. | 0.876 |
EEH64473.1 | adk | HMPREF0044_0210 | HMPREF0044_0420 | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.909 |
EEH64473.1 | cdd | HMPREF0044_0210 | HMPREF0044_0747 | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.918 |
EEH64473.1 | gmk | HMPREF0044_0210 | HMPREF0044_1299 | LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF02872; InterPro: IPR006179. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.910 |