node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEH63291.1 | EEH63679.1 | HMPREF0044_1530 | HMPREF0044_0698 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093. | 0.661 |
EEH63291.1 | EEH64647.1 | HMPREF0044_1530 | HMPREF0044_0384 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | 0.475 |
EEH63291.1 | aspA | HMPREF0044_1530 | HMPREF0044_0940 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.929 |
EEH63291.1 | guaB | HMPREF0044_1530 | HMPREF0044_0693 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.917 |
EEH63291.1 | hpt | HMPREF0044_1530 | HMPREF0044_0347 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.818 |
EEH63291.1 | purA | HMPREF0044_1530 | HMPREF0044_1486 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.999 |
EEH63291.1 | purH | HMPREF0044_1530 | HMPREF0044_0589 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695. | 0.999 |
EEH63291.1 | pyrB | HMPREF0044_1530 | HMPREF0044_1306 | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.435 |
EEH63679.1 | EEH63291.1 | HMPREF0044_0698 | HMPREF0044_1530 | IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093. | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.661 |
EEH63679.1 | guaB | HMPREF0044_0698 | HMPREF0044_0693 | IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.972 |
EEH63679.1 | hpt | HMPREF0044_0698 | HMPREF0044_0347 | IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.936 |
EEH63679.1 | purA | HMPREF0044_0698 | HMPREF0044_1486 | IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.975 |
EEH63679.1 | purH | HMPREF0044_0698 | HMPREF0044_0589 | IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695. | 0.957 |
EEH63788.1 | EEH64647.1 | HMPREF0044_0807 | HMPREF0044_0384 | Hypothetical protein; Pfam: PF00733. | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | 0.938 |
EEH63788.1 | purA | HMPREF0044_0807 | HMPREF0044_1486 | Hypothetical protein; Pfam: PF00733. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.944 |
EEH63788.1 | pyrB | HMPREF0044_0807 | HMPREF0044_1306 | Hypothetical protein; Pfam: PF00733. | Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.944 |
EEH64647.1 | EEH63291.1 | HMPREF0044_0384 | HMPREF0044_1530 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Putative adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.475 |
EEH64647.1 | EEH63788.1 | HMPREF0044_0384 | HMPREF0044_0807 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Hypothetical protein; Pfam: PF00733. | 0.938 |
EEH64647.1 | aspA | HMPREF0044_0384 | HMPREF0044_0940 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.973 |
EEH64647.1 | panD | HMPREF0044_0384 | HMPREF0044_0240 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.932 |